Fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochlorophyllide-serine

نویسندگان

  • I. G. Meerovich
  • I.Yu. Kubasova
  • N. A. Oborotova
  • G. A. Meerovich
  • S. A. Demura
  • A. Brandis
  • V. Rosenbach-Belkin
  • A.Yu. Baryshnikov
  • A. Scherz
چکیده

Study is devoted to investigation of fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochloriphyllide-serine. The peculiarities of its fluorescence excited by different lasers, dynamics and selectivity of accumulation were investigated. Photodynamic therapy of mice and investigation of tissue de-oxygenation during tumor irradiation were performed. It was shown that bacteriochloriphyllide-serine is an effective photosensitizer for PDT and fluorescent diagnostics of tumors.

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تاریخ انتشار 2005